Abstract: In order to achieve efficient purification of industrial organic waste gas,the reaction mecha-nism of the catalytic combustion process of multi-component VOCs and the structure-activity relation-ship of the catalyst were explored. The research progress of catalytic combustion of multi-componentVOCs was summarized. The " mixed reaction" characteristics of different components of VOCs on cata-lysts were summarized. The main factors affecting the catalytic reaction process were analyzed. The de-sign approach of multi-component VOCs catalyst was proposed,and the research direction of multi-component VOCs catalytic control was looked forward. The analysis shows that the " mixing effects" a-mong multi-component VOCs are influenced by the properties of VOCs and catalysts,reaction tempera-ture,reaction products and other factors. Generally," mixing effects" are observed in three forms ofone-way interference,mutual interference and mutual independence. The catalytic reaction behavior ofmulti-component VOCs was significantly affected by the competitive adsorption among VOCs ( or be-tween VOC molecules and reactive oxygen species) and accelerated desorption of products. Close-