To treat mine water containing fluorine and high turbidity, polyaluminium chloride (PAC), compound acid fluoride remover (MT-701), modified aluminum iron silicon polymer fluoride remover (GMS-F6) and composite fluoride remover (DAMW-03) were tested. The results showed that more than 97% of the turbidity of mine water could be removed by four agents. However, PAC and MT-701 could only reduce the concentration of fluoride to 1.2 mg/L and 1.3 mg/L respectively. The fluoride removal effect of DAMW-03 was better than that of GMS-F6. When the addition amount was 140 mg/L, the fluoride concentration was reduced to 0.83 mg/L and 0.95 mg/L after treated by DAMW-03 and GMS-F6, respectively. The fluoride concentration was reduced to 0.95 mg/L when the dosage of DAMW-03 was 120 mg/L, the dosage of flocculant (PAM) was 1.0 mg/L, the stirring speed was 150 r/min, the stirring time was 60 min and the pH was 6~7.