In order to analyze the effect of plate-type anti-arsenic-poisoning SCR denitration catalysts on treating high-arsenic coal-fired flue gas of coal-fired power plant, the denitrification activities of anti-arsenic-poisoning SCR denitration catalyst and fresh catalyst were tested. The catalyst samples were characterized by X-ray fluorescence (XRF), N2 adsorption/desorption, X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The results showed that the denitrification activity of the one-year-used catalyst under 150~450 ℃ was close to that of the fresh catalyst. After one year of operation, the content of arsenic in the catalyst reached 3.06%, mainly in the form of As2O5. The specific surface area of the catalyst decreased slightly. The crystal form of the support TiO2 and the content of V4+ and Oα did not change significantly. The catalyst had no obvious physical and chemical arsenic poisoning, showing good anti-arsenic poisoning performance.