Through literature review and field investigation of an industrial park, the emission reduction potential of main air pollutants was calculated and the primary emission reduction scenario of air pollution control was formulated. The emission reduction scenarios were evaluated via the combined method of analytic hierarchy process and entropy weight. The optimal implementation route of multi-objective decision-making in the whole process of air pollution control was constructed, and the optimal emission reduction scenario was obtained. The prediction results showed that the emission reduction of VOCs, NOx, SO2, NH3 and particulate matter were 2 610.2, 255.1, 96.6, 8.1 and 337.6 t, respectively. The corresponding fixed cost and saved operating cost were 42.2 million yuan per year and 4.199 3 million yuan per year respectively. The feasible measures for the comprehensive control of air pollutants in the industrial park were provided. The multi-objective optimization decision-making method integrating analytic hierarchy process proposed in this study could provide technical support for air pollution management for small or medium-sized industrial parks.